Annual report [Section 13 and 15(d), not S-K Item 405]

Stock-based Compensation - Summary of Stock-Based Compensation Expense (Details)

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Stock-based Compensation - Summary of Stock-Based Compensation Expense (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]      
Total stock-based compensation expense $ 104,446 $ 93,636 $ 69,070
Research and development expenses      
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]      
Total stock-based compensation expense 83,063 73,160 49,713
Selling, general and administrative expenses      
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]      
Total stock-based compensation expense $ 21,383 $ 20,476 $ 19,357